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DAY 1:
Thursday, January 5
2:00 PM – 10:00 PM Registration
3:00 PM – 5:00 PM
Session: Growth, Differentiation and Cancer
Chairs: Steve Elledge, Harvard Univ.
Charles Sherr, St. Jude Children's Research Hospital
Speakers:   Steve Elledge (Harvard): Genetic screens for growth and survival regulators in mammals
Vicki Lundblad (Salk): Replication and resection: regulating access to chromosome ends
Titia de Lange (Rockefeller): Telomeres & Telomerase: The beginning of the end
Iswar Hariharan (Berkeley): Genes that restrict growth and cell proliferation in Drosophila & humans
5:45 PM – 7:00 PM Dinner
7:15 PM – 8:00 PM KEYNOTE SPEAKER: Paul Nurse
8:15 PM – 10:15 PM
Session: Stem cell genetics
Chairs: Judith Kimble, Univ. of Wisconsin, Madison
Janet Rossant, Univ. of Toronto
Speakers:   Judith Kimble (UW Madison): Regulation of germline stem cells in C. elegans
Janet Rossant (U of Toronto): Lineage decisions in the early mammalian embryo- implications for stem cell biology
Margaret Fuller (Stanford): Still in Eden: Male germ line stem cells in the niche maintain a centrosomal Eve
Liheng Li (Stowers Institute): Adult vertebrate stem cells: their niche and molecular regulation
10:00 PM – 12:00 AM Reception

DAY 2:
Friday, January 6
8:00 AM – 10:00 AM
Session: Gene Interactions and Unraveling Complex Traits
Chairs: Aravinda Chakravarti, Johns Hopkins Univ.
Chuck Langley, Univ. of California, Davis
Speakers:   Aravinda Chakravarti (Johns Hopkins): Genetic dissection of a complex disease: Hirschsprung’s disease
Allen Orr (Rochester): Genetic structure of speciation
Trudy Mackay (North Carolina State): The Genetic Architecture of Complex Traits: Lessons From Drosophila
Peter Donnelly (University of Oxford): Fine-structure genetic maps and complex disease mapping
10:30 AM – 12:30 PM
Session: Comparative Genomics
Chairs: Maynard Olson, Univ. of Washington
Eric Green, NHGRI
Speakers:   Eric Green (NHGRI): Deducing mammalian genome function by multi-species comparative sequencing
Bill Gelbart (Harvard): Comparative genome analysis of flies
David Kingsley (Stanford): Fishing for the secrets of vertebrate evolution
Richard Durbin (Sanger Inst.): Comparative genome analysis of worms
12:45 PM – 2:00 PM Lunch
3:00 PM – 5:00 PM
Session: Neurological diseases
Chairs: Susan Lindquist, Whitehead Institute, MIT
Jeremy Berg, NIGMS
Speakers:   Susan Lindquist (Whitehead/MIT): Yeast is a model system for complex problems in neurobiology
Li Hui Tsai (Harvard): Two tales of a kinase:Cdk5 in synaptic plasticity & neurodegeneration
Mario Capecchi (Utah): Modeling Neurological Disorders in the Mouse
Cynthia Kenyon (UCSF): Insulin/IGF-1 signaling and polyglutamine aggregation and toxicity in C. elegans
5:30 PM – 6:45 PM Dinner
7:00 PM – 7:45 PM KEYNOTE SPEAKER: Mary Claire King
8:00 PM – 10:00 PM Poster Session 1

DAY 3:
Saturday, January 7
8:00 AM – 10:00 AM
Session: Technology
Chair: Stan Fields, Univ. of Washington
Speakers:   George Church (Harvard): Genome synthesis and sequencing
Ron Davis (Stanford): New Genomic Technology for Yeast
Lee Hood (Institute for Systems Biology): Systems approaches to human disease
10:00 AM – 10:30 AM Break
10:30 AM – 12:30 PM
Session: New Insights in Epigenetic Phenomena
Chairs: Art Beaudet, Baylor College of Medicine
Barbara Meyer, Univ. of California, Berkeley
Speakers:   Barbara Meyer (Berkeley): X chromosome-wide repression
Vicki Chandler (U Ariz.): Heritable Chromatin Structures are Established Through Trans-interactions Between Tandem Repeats
Steve Henikoff (Fred Hutchinson Cancer Res. Ctr.): Epigenetic patterns generated by assembly of histone variants into nucleosomes
Art Beaudet (Baylor): Mouse models for the Prader-Willi/Angelman/autism imprinted domain
12:45 PM – 2:00 PM Lunch
2:00 PM – 4:00 PM Poster Session 2
4:30 PM – 6:00 PM
Symposium:   Comparative Developmental Biology
Chair: Allan Spradling, Carnegie Institution of Washington
Speakers:  Allan Spradling (Carnegie Institution): Stem cells as a paradigm for model organism research
Jonathan Bard (Univ of Edinburgh): Using bioinformatics to capture tissue similarities across organisms
Utpal Banerjee (UCLA): Drosophila as a model for hematopoietic development
Susan Dutcher (Washington Univ.): Genetic and genomic approaches with Chlamydomonas for understanding ciliary diseases in humans
7:00 PM – 8:30 PM Banquet
8:30 PM – 9:45 PM KEYNOTE SPEAKER: Sydney Brenner
Sponsored by Illumina.

DAY 4:
Sunday, January 8
 
Depart